xenotransplantation相关论文
Successful xenotransplantation of microencapsulated newborn pig parathyroid cells in the treatment o
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SLAM family predicting the initiation potential of human acute lymphoblastic leukemia in NOD/SCID mi
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【摘 要】 猪内源性逆转录病毒(porcine endogenous retrovirus,PERV)是一种以前病毒DNA形式整合入猪基因组中的逆转录病毒,它可随细胞......
AIM: To identify the decreasing effect of xenotransplantion in combination with privileged sites on rejection and death ......
Objective: To investigate the response of the xenograft endothelium in the concordant hamster to rat cardiac xenotranspl......
The Synergistic Effect of HT and Complement Regulatory Proteins in Resisting the Immunological Rejec
Objective:To establish the polytransgenic mice expressing the human HT and complement regulatory proteins (CRPs) and dis......
Short Term Outcome of Human Fetal Ovarian Tissue Cryopreservation and Xenotransplantation to Immunod
This study was designed to evaluate follicular survival and growth after short-term transplantation of cryopreserved and......
肺移植是很多终末期肺疾病唯一有效的治疗方式。由于肺独特的解剖和生理因素,供体肺获取的数量要远小于其他器官,肺源短缺一直以来是......
角膜移植供体缺乏是一个亟待解决的难题.研究表明,与其他系统的器官移植相比较,角膜组织的免疫赦免特性使角膜移植不易发生免疫排......
Successful xenotransplantation of microencapsulated newborn pig parathyroid cells in the treatment o
Objective To study the effect of xenotransplantation with pig parathyroid cells,which was prepared using cell microenca......
Cytokine production during the inhibition of acute vascular rejection in a concordant hamster-to-rat
Background The aim of the current study was to investigate the role of interleukin (IL)-2, interferon (IFN)-γ, IL-4 and......
SLAM family predicting the initiation potential of human acute lymphoblastic leukemia in NOD/SCID mi
Background The SLAM family recently has been reported to show an important biological role in lymphocyte development an......
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Down-regulation of αGal epitopes by co-transfection of α1,3-galactosidase gene and α1,2-fucosyltrans
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Identification of the candidate genes associated with cellular rejection in pig-to-human xenotranspl
To identify the genes associated with cellular rejection in pig-to-human xenotransplantation, the suppression subtractiv......
BACKGROUND:?A major barrier to the clinical application of xenotransplantation as a treatment option for patients is T c......
Achievement of Cellular Immunity and Discordant Xenogeneic Tolerance in Mice by Porcine Thymus Graft
Specific cellular immune tolerance may be essential for successful xenotransplantation in humans. Thymectomized (ATX), T......
采用豚鼠对大鼠异种心脏移植模型,应用化学发光法和比色法分别测定了移植心切取时、林格氏液(4℃)保存1小时和移植后1小时移植心整......
本实验建立了豚鼠肾灌注模型,观察了32例豚鼠肾灌注后SD大鼠天然抗体的动态变化。结果32例豚鼠肾灌注手术均获成功,SD大鼠体内天然抗......
采用Heron袖套法进行异种(小鼠→大鼠)心脏移植,异位移植于颈部皮下,供体主动脉接受体颈内动脉,供体肺动脉接受体颈外静脉,并对手......
To lay background for studying rejection mechanisms in xenotransplantation and developing the strategies for interventio......
同种器官移植成功率的提高导致了供体器官的严重短缺.采用解剖学上与人类相近的动物,比如猪的器官可以解决这种危机.但从猪到人的......
目的 探讨建立人-大鼠异种毛囊移植的可行性及局部辅助应用他克莫司的效果.方法 以人头皮毛囊为供体,Wistar大鼠为受体,将黑色人头......
Successful xenotransplantation of microencapsulated newborn pig parathyroid cells in the treatment o
Objective To study the effect of xenotransplantation with pig parathyroid cells, which was prepared using cell microenca......
目的 探讨中华鳖胰岛细胞分离、提取方法及对其功能评价,为临床胰岛移植探索一种新的供体来源.方法 采用胶原酶消化分离中华鳖胰岛......
The Effects of PDTC plus Leflunomide and Cyclosporine on the NF-кB Signaling Pathway in Mouse-to-rat
In this study,the effects of pirrolidine dithiocarbamate (PDTC) plus leflunomide (Lef) models were investigated.NIH mice......
Cytokine production during the inhibition of acute vascular rejection in a concordant hamster-to-rat
Background The aim of the current study was to investigate the role of interleukin (IL)-2, interferon (IFN)-γ, IL-4 and......
Down-regulation of αGal epitopes by co-transfection of α1,3-galactosidase gene and α1,2-fucosyltrans
The polycarbohydrate structure of Galα1- 3Galβ1-4GluNAc-R (known as αGal epitopes of xenoantigen), produced by α1-3-......
目的:摸索X-GVHD模型的合适小鼠品系,建立稳定的“人-鼠”X-GVHD模型。方法:选取了裸鼠、NOD/SCID经亚致死剂量γ射线全身照射后,腹腔输......
目的 观察Th22细胞在小鼠外周神经异种移植排斥反应中的动态变化. 方法 40只C57小鼠按随机数字表法分为对照组和实验组,每组20只.......
Establishment of Reproducible Xenotransplantation Model of T Cell Acute Lymphoblastic Leukemia in NO
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To elucidate the structures of SLA-DR (swine leukocyte antigen DR) genes of three Chinese pig strains (Gz, Bm and Yn), t......
Comparison of Morphology and Microstructural Components of Hepatic Portal Vein between Human and Pig
In order to provide morphological data and theoretical basis for pig-to-human hepatic xenotransplantation, the differenc......
胰岛移植能够纠正DDM的高血糖并减少糖尿病相关并发症,临床广泛应用将造成尸源性胰腺供体严重不足,动物来源的胰岛将成为今后胰岛......
目的:评估新生猪胰岛移植治疗1型糖尿病方法的安全性和有效性。方法:所有22例病人均接受经肝动脉新生猪胰岛移植治疗,移植后病人接受......
目的探讨猪-人非协调性异种移植中超急性排斥反应(HAR)及静脉注射用免疫球蛋白(IVIG)抑制HAR的作用机制.方法以体外游离器官血液灌......
目的采用改良袖套法建立小鼠→大鼠颈部异位异种心脏移植动物模型,动态观察移植心脏病理特征。方法NIH小鼠和Wistar大鼠作为供、受......
目的:通过对猪与人胆总管生物力学特性的比较研究,探讨其相互间的关系,从生物力学方面评价猪胆总管作为人胆管移植替代材料的可行......
为建立异种心脏移植急性血管排斥反应期动物模型,选择豚鼠和SD大鼠分别作为供体和受体.豚鼠升主动脉与大鼠腹主动脉端侧吻合,豚鼠......
在全球范围内,因终末期器官衰竭而需要器官移植的患者人数不断增加,但从已故或活体捐赠者获得的器官数量非常有限。因此,利用猪器......
目的探讨豚鼠至大鼠异种原位肝移植中肝下下腔静脉套管的改进方法。方法豚鼠和SD大鼠各40只分别作为供、受体,随机分为实验组和对......
目的 建立腹主动脉补丁缝合术的异种移植模型以及术后免疫排斥监测平台。方法 将野生型巴马猪的颈动脉,修剪成约2.5 cm×1.0 c......
器官移植是治疗终末期器官衰竭的最有效手段,但供器官严重匮乏已成为器官移植发展的最大障碍,异种器官移植为解决这一问题开辟了新思......
目的观察微囊化兔坐骨神经组织细胞移植对脊髓半横断后脊神经节P物质(SP)表达的变化。方法将实验动物分为对照组、损伤组、细胞悬液......
目的:探讨异种肝细胞移植对大鼠急性肝功能衰竭的治疗效果.方法: 切除大鼠90%肝脏,建立急性肝功能衰竭模型.分离异种豚鼠和同种异......
目的 探讨猪内皮细胞与人血清作用后基因表达的变化。方法 猪内皮细胞系PIEC被含20%人血清的培养基作用2.5小时作为实验组,对照组为含......
目的研究中华眼睛蛇蛇毒因子(CCV)及复方丹参在异种移植中的作用.方法采用颈部套袖法建立豚鼠对大鼠心脏异种移植模型.于术前24 h......
目的建立一种猪到人异种心脏移植超急性排斥反应实验模型。方法 8只广西巴马猪正中切口锯开胸骨进胸,肝素化,完整剪取猪心脏,用4℃......
目的 探索重组腺病毒载体(Recombinantadenovirus,rAdv)介导CTLA4Ig基因转染猪皮异种移植免疫耐受的分子机制。方法 构建CTLA4Ig重组......