xenotransplantation相关论文
由于猪的诸多生理和遗传特征与人类近似,猪一直被认为是理想的异种器官移植候选供体动物.但是物种之间严重的免疫不相容是影响猪到......
Characterization of PERV in a new conserved pig herd as potential donor animals for xenotransplantat
Background Xenotransplantation has drawn increased attention in recent years as a potential solution to the scarcity of ......
We conducted a large-scale survey on the existence and expression status of porcine endogenous retrovirus (PERV)in seven......
Growth factor improving survival of rat islet xenografts using microencapsulation in prevascularized
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Transgenic expression of human cytoxic T-lymphocyte Associated antigen4-Immunoglobulin (hCTLA4Ig) by
Porcine skin is frequently used as a substitute of human skin to cover large wounds in clinic practice of wound care.In ......
Porcine skin is frequently used as a substitute of human skin to cover large wounds in clinic practice of wound care.In ......
Successful xenotransplantation of microencapsulated newborn pig parathyroid cells in the treatment o
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SLAM family predicting the initiation potential of human acute lymphoblastic leukemia in NOD/SCID mi
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Organ shortage is a major bottleneck in allotransplantation and causes many wait-listed patients to die or become too si......
Comprehensive Analysis of Leukocytes, Vascularization and Matrix Metalloproteinases in Human Menstru
In our previous study, menstrual-like changes in mouse were provoked through the pharmacologic withdrawal of progest......
Down-regulation of αGal epitopes by co-transfection of α1,3-galactosidase gene and α1,2-fucosyltrans
The polycarbohydrate structure of Galα1- 3Galβ1-4GluNAc-R (known as αGal epitopes of xenoantigen), produced by α1-3-......
Generation of GGTA1 biallelic knockout pigs via zinc-finger nucleases and somatic cell nuclear trans
Genetically modified pigs are valuable models of human disease and donors of xenotransplanted organs.Conventional gene t......
Achievement of Cellular Immunity and Discordant Xenogeneic Tolerance in Mice by Porcine Thymus Graft
Specific cellular immune tolerance may be essential for successful xenotransplantation in humans. Thymectomized (ATX), T......
目的:探讨经玻璃化法和慢速程序冷冻法冷冻保存的成人卵巢皮质异种皮下移植后卵泡生长发育和雌激素分泌情况。方法:将人类卵巢组织......
The Effects of PDTC plus Leflunomide and Cyclosporine on the NF-кB Signaling Pathway in Mouse-to-rat
In this study,the effects of pirrolidine dithiocarbamate (PDTC) plus leflunomide (Lef) models were investigated.NIH mice......
Establishment of Reproducible Xenotransplantation Model of T Cell Acute Lymphoblastic Leukemia in NO
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The Synergistic Effect of HT and Complement Regulatory Proteins in Resisting the Immunological Rejec
Objective:To establish the polytransgenic mice expressing the human HT and complement regulatory proteins (CRPs) and dis......
【摘 要】 猪内源性逆转录病毒（porcine endogenous retrovirus，PERV）是一种以前病毒DNA形式整合入猪基因组中的逆转录病毒，它可随细胞......
AIM: To identify the decreasing effect of xenotransplantion in combination with privileged sites on rejection and death ......
Objective: To investigate the response of the xenograft endothelium in the concordant hamster to rat cardiac xenotranspl......
The Synergistic Effect of HT and Complement Regulatory Proteins in Resisting the Immunological Rejec
Objective:To establish the polytransgenic mice expressing the human HT and complement regulatory proteins (CRPs) and dis......
Short Term Outcome of Human Fetal Ovarian Tissue Cryopreservation and Xenotransplantation to Immunod
This study was designed to evaluate follicular survival and growth after short-term transplantation of cryopreserved and......
肺移植是很多终末期肺疾病唯一有效的治疗方式。由于肺独特的解剖和生理因素，供体肺获取的数量要远小于其他器官，肺源短缺一直以来是......
角膜移植供体缺乏是一个亟待解决的难题.研究表明,与其他系统的器官移植相比较,角膜组织的免疫赦免特性使角膜移植不易发生免疫排......
Successful xenotransplantation of microencapsulated newborn pig parathyroid cells in the treatment o
Objective To study the effect of xenotransplantation with pig parathyroid cells,which was prepared using cell microenca......
Cytokine production during the inhibition of acute vascular rejection in a concordant hamster-to-rat
Background The aim of the current study was to investigate the role of interleukin (IL)-2, interferon (IFN)-γ, IL-4 and......
SLAM family predicting the initiation potential of human acute lymphoblastic leukemia in NOD/SCID mi
Background The SLAM family recently has been reported to show an important biological role in lymphocyte development an......
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Down-regulation of αGal epitopes by co-transfection of α1,3-galactosidase gene and α1,2-fucosyltrans
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Identification of the candidate genes associated with cellular rejection in pig-to-human xenotranspl
To identify the genes associated with cellular rejection in pig-to-human xenotransplantation, the suppression subtractiv......
BACKGROUND:?A major barrier to the clinical application of xenotransplantation as a treatment option for patients is T c......
Achievement of Cellular Immunity and Discordant Xenogeneic Tolerance in Mice by Porcine Thymus Graft
Specific cellular immune tolerance may be essential for successful xenotransplantation in humans. Thymectomized (ATX), T......
采用豚鼠对大鼠异种心脏移植模型,应用化学发光法和比色法分别测定了移植心切取时、林格氏液(4℃)保存1小时和移植后1小时移植心整......
本实验建立了豚鼠肾灌注模型，观察了32例豚鼠肾灌注后SD大鼠天然抗体的动态变化。结果32例豚鼠肾灌注手术均获成功，SD大鼠体内天然抗......
采用Heron袖套法进行异种(小鼠→大鼠)心脏移植,异位移植于颈部皮下,供体主动脉接受体颈内动脉,供体肺动脉接受体颈外静脉,并对手......
To lay background for studying rejection mechanisms in xenotransplantation and developing the strategies for interventio......
同种器官移植成功率的提高导致了供体器官的严重短缺.采用解剖学上与人类相近的动物,比如猪的器官可以解决这种危机.但从猪到人的......
目的 探讨建立人-大鼠异种毛囊移植的可行性及局部辅助应用他克莫司的效果.方法 以人头皮毛囊为供体,Wistar大鼠为受体,将黑色人头......
Successful xenotransplantation of microencapsulated newborn pig parathyroid cells in the treatment o
Objective To study the effect of xenotransplantation with pig parathyroid cells, which was prepared using cell microenca......
目的 探讨中华鳖胰岛细胞分离、提取方法及对其功能评价,为临床胰岛移植探索一种新的供体来源.方法 采用胶原酶消化分离中华鳖胰岛......
The Effects of PDTC plus Leflunomide and Cyclosporine on the NF-кB Signaling Pathway in Mouse-to-rat
In this study,the effects of pirrolidine dithiocarbamate (PDTC) plus leflunomide (Lef) models were investigated.NIH mice......
Cytokine production during the inhibition of acute vascular rejection in a concordant hamster-to-rat
Background The aim of the current study was to investigate the role of interleukin (IL)-2, interferon (IFN)-γ, IL-4 and......
Down-regulation of αGal epitopes by co-transfection of α1,3-galactosidase gene and α1,2-fucosyltrans
The polycarbohydrate structure of Galα1- 3Galβ1-4GluNAc-R (known as αGal epitopes of xenoantigen), produced by α1-3-......
目的：摸索X-GVHD模型的合适小鼠品系，建立稳定的“人-鼠”X-GVHD模型。方法：选取了裸鼠、NOD／SCID经亚致死剂量γ射线全身照射后，腹腔输......
目的 观察Th22细胞在小鼠外周神经异种移植排斥反应中的动态变化. 方法 40只C57小鼠按随机数字表法分为对照组和实验组,每组20只.......
Establishment of Reproducible Xenotransplantation Model of T Cell Acute Lymphoblastic Leukemia in NO
...
To elucidate the structures of SLA-DR (swine leukocyte antigen DR) genes of three Chinese pig strains (Gz, Bm and Yn), t......
Comparison of Morphology and Microstructural Components of Hepatic Portal Vein between Human and Pig
In order to provide morphological data and theoretical basis for pig-to-human hepatic xenotransplantation, the differenc......
胰岛移植能够纠正DDM的高血糖并减少糖尿病相关并发症,临床广泛应用将造成尸源性胰腺供体严重不足,动物来源的胰岛将成为今后胰岛......
目的：评估新生猪胰岛移植治疗1型糖尿病方法的安全性和有效性。方法：所有22例病人均接受经肝动脉新生猪胰岛移植治疗,移植后病人接受......
